University of Manchester
Browse

Figure 4B Raw data - <b>Increased </b><b><i>in vivo</i></b><b> transduction of AAV-9 cargo in Alport podocytes</b>

Download (13.62 kB)
dataset
posted on 2025-06-11, 11:33 authored by Maryline FresquetMaryline Fresquet, Emily WilliamsEmily Williams, gema bolas, Rachel LennonRachel Lennon
<p dir="ltr">Raw dataset and analysis for Figure 4B:</p><p dir="ltr"><br></p><p dir="ltr"><b>Figure 4: AAV9-GFP transduction in kidneys of 8, 10, 12-week-old wild type and Alport mice injected with saline or the high dose (1.65 x 10</b><sup><strong>14</strong></sup><b> vg/kg).</b> <b>B</b>) Urinary ACR performed on 10-week-old mice (WT and Alport) after injection of either saline or high-dose of AAV9-GFP. Urine was collected for baseline read-out at 10 weeks (before injection), mid-point at 12 weeks (2 weeks post-injection) and endpoint at 14 weeks (4 weeks post-injection).</p>

Funding

Reprogramming Extracellular Matrix

Wellcome Trust

Find out more...

How do tissues connect? Elucidating a newly identified matrix adhesion system

Wellcome Trust

Find out more...

Kidney Research UK and The Stoneygate Trust (Alport Research Hub)

Understanding how cells invade through basement membrane in vivo

National Institute of General Medical Sciences

Find out more...

History

Research ethics approval number

Project License PP4262564

Usage metrics

    School of Biological Sciences

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC