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Figure 4E Raw data - Increased in vivo transduction of AAV-9 cargo in Alport podocytes

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posted on 2025-06-11, 11:37 authored by Maryline FresquetMaryline Fresquet, Emily WilliamsEmily Williams, gema bolas, Rachel LennonRachel Lennon

Raw dataset and analysis for Figure 4E:


Figure 4: AAV9-GFP transduction in kidneys of 8, 10, 12-week-old wild type and Alport mice injected with saline or the high dose (1.65 x 1014 vg/kg). E) The quantification of GFP-positive podocytes (%) is displayed for the two phenotypes WT (left) and Alport mice (right), injected with either saline (light grey bars) or high dose of AVV9-GFP (dark grey bars) (n=2-4 mice per group and per condition). Data are presented as mean ± SEM. P value <0.005 (**).

Funding

Reprogramming Extracellular Matrix

Wellcome Trust

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How do tissues connect? Elucidating a newly identified matrix adhesion system

Wellcome Trust

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Kidney Research UK and The Stoneygate Trust (Alport Research Hub)

Understanding how cells invade through basement membrane in vivo

National Institute of General Medical Sciences

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Project License PP4262564

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