<p dir="ltr">The National Institute for Health and Care Excellence (NICE) guidelines on self-harm (2022) aim to improve the quality of care of individuals who self-harm in all services and settings. A rapid review of the literature revealed an absence of research on social workers' implementation of the guidelines, and their implementation with vulnerable groups. This study aims to bridge this knowledge gap. Children in care are at increased risk of self-harm with risk rates between two and four-fold higher than children without care experience. However, very little is known about the assessment and management of self-harm in this group. This study explores children's social workers' knowledge of the NICE guidelines on self-harm and their opportunities, capabilities and motivations to implement them with children in care, using semi-structured interviews.</p>