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Research data for 'The role of kinesin-1 in neuronal dense core vesicle transport, locomotion and lifespan regulation in C. elegans'

dataset
posted on 2024-10-01, 10:48 authored by Anna Gavrilova, Astrid Boström, Nickolay Korabel, Gino B. Poulin, Sergei Fedotov, Victoria AllanVictoria Allan

The data comprises:

  1. Original data showing dense core vesicle movement imaged in the ALA neuron in C. elegans in wildtype background (ida-1::GFP), and in kinesin-1 mutant backgrounds: unc-116(rh24sb79), klc-1(ok2609) and klc-2(km11). The original movie TIFF files and kymographs for each strain are included as zip files. The associated tracking data from KymoButler are included as excel files. This is the original data used for figures 2, 3, 4, S3, S4, S5, S6 and table 1 of the associated paper.
  2. Excel files of the original scoring data and statistical analysis of lifespan, aldicarb sensitivity and levamisole sensitivity are included, which relate to the text and figures 5c, 5d and figure 6.

Funding

Wellcome Trust 4-year PhD Programme in Quantitative and Biophysical Biology

Wellcome Trust

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Manchester DTP3

Biotechnology and Biological Sciences Research Council

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Modelling anomalous transport of nanoparticles and DNA repair to improve radiotherapy

Engineering and Physical Sciences Research Council

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