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Figure 1a preQ0 to preQ1.png (94.04 kB)
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Figure 1a preQ0 to preQ1.cdx (6.03 kB)
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Figure 1b.png (731.05 kB)
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Figure 1b.cdx (51.55 kB)
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Fig 1c Quef-Y5Y.pse (2.03 MB)
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Figure 1c QueF-Y5Y.png (658.03 kB)
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Figure 1 components

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posted on 2022-08-31, 15:43 authored by Christopher BlanfordChristopher Blanford, Yuhei Hayamizu, Abubaker Mohamed, Sam P. deVisser

Figure 1a The natural reaction of QueF in vivo from preQ0 to preQ1 drawn with ChemDraw 21.

Figure 1b Schematic representation of an antiparallel β-sheet formation of the Y5Y fusion protein drawn with ChemDraw 21.

Figure 1c Homology model of preQ0 (green sticks) docked in QueF (black ribbon) with a short serine linker (pink) added followed by the Y5Y chain (red). Model created using PDB 4GHM and I-TASSER in PyMOL 2.0.

Funding

Manchester-Bangor DTP2

Biotechnology and Biological Sciences Research Council

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