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Figure 3C Raw data - Increased in vivo transduction of AAV-9 cargo in Alport podocytes

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posted on 2025-06-11, 11:31 authored by Maryline FresquetMaryline Fresquet, Emily WilliamsEmily Williams, gema bolas, Rachel LennonRachel Lennon

Raw images for Figure 3C:


Figure 3: AAV9-GFP transduction in kidneys of wild type and Alport mice injected at low (6.6x1012 vg/kg), medium (3.3x1013 vg/kg) and high (1.65x1014 vg/kg) dose. In total, 6 (3 WT and 3 Col4a5 KO) 8-week-old mice per group were injected with either AAV9-GFP or saline. C) Representative immunofluorescence images of glomerular sections where DAPI is in grey, WT1 (podocyte marker) in magenta and GFP in green. Scale bars = 20 µm.

Funding

Reprogramming Extracellular Matrix

Wellcome Trust

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How do tissues connect? Elucidating a newly identified matrix adhesion system

Wellcome Trust

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Kidney Research UK and The Stoneygate Trust (Alport Research Hub)

Understanding how cells invade through basement membrane in vivo

National Institute of General Medical Sciences

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Project License PP4262564

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