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Figure 4D Raw data - Increased in vivo transduction of AAV-9 cargo in Alport podocytes

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posted on 2025-06-11, 11:35 authored by Maryline FresquetMaryline Fresquet, Emily WilliamsEmily Williams, gema bolas, Rachel LennonRachel Lennon

Raw images for Figure 4D:

Figure 4: AAV9-GFP transduction in kidneys of 8, 10, 12-week-old wild type and Alport mice injected with saline or the high dose (1.65 x 1014 vg/kg). D) High-resolution images showing the GFP localization in WT and Alport glomeruli from mice injected with the high dose of AAV9-GFP. White arrows highlight colocalization of the GFP vector within the podocytes and red arrows, the localization of GFP with other glomerular cells.

Funding

Reprogramming Extracellular Matrix

Wellcome Trust

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How do tissues connect? Elucidating a newly identified matrix adhesion system

Wellcome Trust

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Kidney Research UK and The Stoneygate Trust (Alport Research Hub)

Understanding how cells invade through basement membrane in vivo

National Institute of General Medical Sciences

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Research ethics approval number

Project License PP4262564

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