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DATASET
Figure 1 - cell responses & lmax.xlsx (2.77 MB)
TEXT
Opsin_Fit-README.md (4.78 kB)
TEXT
opsin-receptor-fitting-analysis.Rproj (0.21 kB)
TEXT
1.extract_and_transform.R (2.79 kB)
TEXT
2.fitting_procedure.R (2.66 kB)
TEXT
3.fig_bootstrap_results.R (2.74 kB)
TEXT
4.fig_RSS_per_lmax.R (5.15 kB)
TEXT
5.sigmoid_fits_plots.R (4.75 kB)
TEXT
calc_sum_log_photons_gov.R (1.6 kB)
TEXT
create_govardovskii_template.R (0.86 kB)
TEXT
lmax_based_5p_fitting.R (1.67 kB)
TEXT
power_to_photons.R (0.35 kB)
DATASET
responses.xlsx (18.58 kB)
DATASET
spectra.xlsx (323.56 kB)
TEXT
Figure 2 - ReadMe.txt (1.04 kB)
TEXT
plotsspecs.m (1.26 kB)
TEXT
plotvalidation.m (2.34 kB)
TEXT
calculateerrors.m (4.21 kB)
.MAT
calibration.mat (4.64 kB)
.MAT
validation.mat (633.77 kB)
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36 files

Research data and scripts for manuscript "Beyond Lux: Methods for Species and Photoreceptor-Specific Quantification of Ambient Light for Mammals"

Version 2 2024-10-04, 15:51
Version 1 2023-10-23, 15:22
journal contribution
posted on 2024-10-04, 15:51 authored by Richard McdowellRichard Mcdowell, Altug DidikogluAltug Didikoglu, Tom WoeldersTom Woelders, Mazie Gatt, Saba Notash, Finn Moffat, Roelof Hut, Timothy M. Brown, Robert J Lucas

These files contain the raw data, analysis and scripts used to create the figures for the paper: Beyond Lux: Methods for Species and Photoreceptor-Specific Quantification of Ambient Light for Mammals

Figure 1 Data - Mammalian melanopsin spectral sensitivities

Raw & normalised cell response data:

  • Figure 1 - cell responses & lmax.xlsx

lmax fitting script:

  • Opsin_Fit-README.md
  • opsin-receptor-fitting-analysis.Rproj
  • 1.extract_and_transform.R
  • 2.fitting_procedure.R
  • 3.fig_bootstrap_results.R
  • 4.fig_RSS_per_lmax.R
  • 5.sigmoind_fits_plots.R
  • calc_sum_log_photons_gov.R
  • create_govardovskii_template.R
  • lmax_based_5p_fitting.R
  • power_to_photons.R
  • responses.xlsx
  • spectra.xlsx


Figure 2 Data - Cross-species light dosimeter validation

  • Figure 2 - ReadMe.txt

Functions:

  • plotspecs.m
  • plotvalidation.m
  • calculateerrors.m

Workspaces (Used by functions above):

  • calibration.mat
  • validation.mat


Figure 3 Data - Irradiance response curves for circadian phase shifting in C57 wild-type mouse

  • Figure 3 - raw data.xlsx


Figure 4 Data - Cross-species α-opic EDIs across different light sources

  • Figure 4 - raw data.xlsx
  • Figure 4 - SolarAngle.R
  • Figure 4 - SolarAngle.Rdata


Supplementary Figure 1 - Pre-Receptoral Filtering Data

  • Pre_R_Filter-Cornea-1-Norm_cornea_trans_data.csv
  • Pre_R_Filter-Cornea-2-Transf_Norm_Spline_Norm_cornea_trans_data.csv
  • Pre_R_Filter-Cornea-2-Transf_Norm_SplineCubic_Norm_cornea_trans_data.csv
  • Pre_R_Filter-Cornea-3-cornea.trans.data.csv
  • Pre_R_Filter-Lens-1-Norm_lens_trans_data.csv
  • Pre_R_Filter-Lens-2-Transf_Norm_Spline_Norm_lens_trans_data.csv
  • Pre_R_Filter-Lens-2-Transf_Norm_SplineCubic_Norm_lens_trans_data.csv
  • Pre_R_Filter-Lens-3-lens.trans.data.csv
  • Pre_R_Filter-Vitreous-1-Norm_vitreous_trans_data.csv
  • Pre_R_Filter-Vitreous-2-Transf_Norm_Spline_Norm_vitreous_trans_data.csv
  • Pre_R_Filter-Vitreous-2-Transf_Norm_SplineCubic_Norm_vitreous_trans_data.csv
  • Pre_R_Filter-Vitreous-3-vitreous.trans.data.csv



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