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<p><strong>Supplementary Video 2. Multiple bacteria may successfully invade the host cell from a single aggregate</strong> Representative confocal microscopy video of 3 biological replicates of HeLa cells infected with Lm<em>-</em>dsRed<em>-PactA-</em>GFP MOI=20 for 2 hours. Video shows an aggregate of 4 bacteria invading a HeLa cell and establishing a successful replicative invasion. Scale bar 10 μm</p>