Infected Blood Inquiry 2025 paper STATA syntax code includes main analysis using Cox proportional hazards modelling and secondary analysis using Royston-Parmer flexibleparametric survival models to estimate the within patient expected years of life lost (YLL) for HIV/HCV co-infected and HCV only infected exposure groups

<p dir="ltr">In 2017, the UK government announced a public inquiry to be chaired by Sir Brian Langstaff into the impact that using infected blood and/or blood products had on Patients with Bleeding Disorders PwBDs, transfusion recipients and their families. This project supported the Statistical Expert Group (SEG) to provide evidence to the Inquiry. Specifically, the Infected Blood Inquiry (IBI) aim of understanding the longer-term health risks associated with exposure to contaminated blood and/or blood products between 1970 and 1991 in PwBDs. The follow project folder will contains stata analysis code and additional documents, used to perform the main analysis of the paper that was subsequently produced from the evidence provided to SEG. The analysis uses data from The UK Haemophilia Centre Doctors’ Organisation (UKHCDO), who collects information on all registered PwBDs in England, Scotland, Wales, and NI within the National Haemophilia Database (NHD). This is not publicly available.</p><p dir="ltr">The attached is the statistical analysis code used to investigate the survival of PwBDs who were exposed to contaminated products. It includes the main analysis (a Cox Proportional Hazard Model) and the secondary analysis of Years of Life Lost estimating expected years of life lost within a particular patient group (PwBDs) through the use of a Royston-Parmer Flexible Parametric Survival Model. Further details including explanation of methods can be found in main text and supplementary material of Gittins et al (current working title) <b><i>"</i></b><i>Longer-term survival of UK people with bleeding disorders, alive at 1 January 1992, who were infected by Human Immunodeficiency Virus and/or Hepatitis C Virus through contaminated blood products/pooled plasma between 1970-1991.</i><i>"</i></p>